Change the Approver once a claim has been submitted

Approvers are set up in Access Expense and assigned to Approval routes for certain users and Expense Types. Unfortunately, if a claim has been submitted, you are not able to amend the approver. The claim would need to be un-submitted (or rejected) and processed again by the claimant once the approval route has been updated.
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However, it is possible to set permission to approve on behalf of another person and so work around the situation if required